A multifaceted intervention, aiming at several aspects of DM management, should probably be more effective to improve care and control of DM on a primary health care level, but it would demand conjugated efforts from government and society to improve issues such as availability of multiprofessional teams, availability of better insulins and oral drugs, availability of reagent strips for self-monitoring of blood glucose, better access to diabetes education, and others. The gene discussed is INS; the disease is diabetes mellitus.