PKD2L1 and infection: Given the relatively long duration of the asymptomatic infection stage, the duration of immunity and the role of PKDL (which could slow down the initial decline seen in the first two years of control (Le Rutte et al., 2016)), the decline in VL incidence due to IRS is expected to be seen only months to years after the start of IRS; hence data spanning a longer time frame would be valuable for future studies.