CDR1 and early-onset autosomal dominant Alzheimer disease: CiRS-7 was firstly found in large amounts in human brain tissue and was also termed CDR1 (cerebellum degeneration-related antigen 1, CDR1,also known as CDR34) because of its transcription in the antisense orientation with respect to the CDR1 gene, which has been implicated to be crucial in autoimmune neurologic disorders like Alzheimer’s disease [69–71].