Plasma LECT2 levels were significantly correlated with VFA after adjustment for age regardless of: age (<65 years r = 0.45, P < 0.001; ≥65 years: r = 0.41, P = 0.001); the presence of dyslipidemia (r = 0.34, P = 0.009) versus non-dyslipidemia (r = 0.41, P < 0.001) or hypertension (r = 0.50, P < 0.001) versus normotension (r = 0.42, P = 0.001); and any medication use (r = 0.50, P < 0.001) versus no medication use (r = 0.39, P < 0.001). Here, LECT2 is linked to metabolic syndrome.