Although antidementia medications (acetylcholinesterase inhibitors and memantine) are recommended as the first-line treatments for behavioural and psychological symptoms of dementia, [1] psychotropic drugs (antidepressants, antipsychotics and benzodiazepines and related drugs; BZDRs) are frequently used among persons with dementia or Alzheimer’s disease (AD; the most common form of dementia). This evidence concerns the gene ACHE and Alzheimer disease.