During infection with L. donovani gp63 cleaves Dicer1, that could impact in post-transcriptional regulation of host-mRNAs by miRNA/RNP interactions, as showed by Dicer1-mediated inhibiting of pre-miR-122 processing and downregulation of miR-122 activity in Huh7 cells28. This evidence concerns the gene RNPC3 and infection.