MYBL2 and breast cancer: This finding was confirmed by comparing RNA and exome sequence results from TCGA breast cancer dataset, which revealed a significant association between MYBL2 and A3B expression and somatic mutations in that, once mutations occurred in tumors, there were twice as many C-to-T as well as total mutations per exome in higher MYBL2–expressing cells compared with lower MYBL2–expressing cells (Fig. 3D and Supplementary Fig. S1).