CXCL8 and ovarian carcinoma: Proteins encoded by NFκB target genes include anti-apoptotic, growth-promoting, proinvasive, proangiogenic and immunesuppressive proteins, exemplified by BCLX-L, IL-6, IL-8, VEGF, and PD-1L, which explains its multifaceted role in ovarian cancer progression and therapy resistance (268, 271).