IFNG and ovarian carcinoma: Another cytokine with beneficial immune stimulatory and antitumor effects in ovarian cancer patients is interferon (IFN)γ (133–136) consistent with the observation that IFNγ can prevent the skewing of monocyte differentiation by ovarian cancer ascites from immune stimulatory IL-10lowIL-12high macrophages to TAM-like IL-10highIL-12low cells and to abrogate the suppressive effect of ovarian cancer ascites on the inducibility by TLRs ligands of IL-12 secretion (127) (see text footnote 1).