IL-10 produced by all immune cells, including monocytes, macrophages, mast cells, granulocytes, T and B lymphocytes, dendritic cells, keratinocytes and tumour cells induces anti-inflammatory or antitumor activity by enhancing B-cell proliferation, antibody production and survival, NF-kb inhibition, and also inhibiting production of TNF-alfa,IL-6,IL-12. Here, IL6 is linked to neoplasm.