It is recruited to the tumour microenvironment by chemokines such as CXCL8,CXCL1,CXCL2, and CXCL3 by the production of inflammatory mediators such as TNF-Alfa, MIP-1 ALFA, H202, and NO that are cytotoxic to tumour cells. The gene discussed is CXCL3; the disease is neoplasm.