PPARG and atherosclerosis: Overall, the PPAR-γ non-genomic actions, the PPAR-γ genomic functions, and the modulation of the cross talk between PPAR-γ and other key survival pathways support the pleiotropic functions of PPAR-γ that include fat cell formation and differentiation (4, 70–73), glucose and lipid homeostasis (74–77), atherosclerosis regulation (78), and anti-inflammatory effects (79, 80).