Interestingly, several signaling pathways, such as arachidonic acid metabolism, circadian rhythm, linoleic acid metabolism, PPAR signaling pathway, sphingolipid metabolism, steroid biosynthesis, tryptophan metabolism and tyrosine metabolism were significantly changed in NAFLD in both lncRNA target analysis and mRNA enrichment analysis (Figure 4). Here, PPARA is linked to metabolic dysfunction-associated steatotic liver disease.