However, in another case-control study analyzing the association between the TP53 gene rs1042522 C>G polymorphism and retinoblastoma risk in the Chinese Han population, Chen et al. found that no in allele or genotypic frequencies of the TP53 gene rs1042522 C>G between cases (n=168) and controls (n=185) [42]. The gene discussed is TP53; the disease is retinoblastoma.