CXCR5 and scrapie: In order to determine the effects of conventional DC-specific CXCR5-deficiency on oral prion pathogenesis, groups of CXCR5ΔDC mice and CXCR5F/F mice were orally exposed to ME7 scrapie prions and Peyer's patches, MLN, and spleens collected at intervals afterwards (n = 4/group).