Similarly, PDGFB, a master regulator of vasculogenesis during development and tumorigenesis (Cao et al, 2011; Xue et al, 2011; Cao, 2013), is known to promote human MSC proliferation and migration (Cheng et al, 2013; Sun et al, 2013) and regulate MSC recruitment and differentiation into a pericyte phenotype in tumors, thereby enhancing tumor angiogenesis (Abramsson et al, 2003; Furuhashi et al, 2004). This evidence concerns the gene PDGFB and neoplasm.