In contrast to LOX and LOXL2, only moderately elevated expression compared to the basal levels was observed for LOXL1 and LOXL4 in IPF lungs with bronchial epithelium, fibrotic foci and to a lesser extent large vessel walls being the main sites of expression (Fig. 4b). The gene discussed is LOXL2; the disease is idiopathic pulmonary fibrosis.