IDH1 and central nervous system cancer: The univariate Cox regression revealed that isocitrate dehydrogenase 1 (IDH1, hazards ratio (HR) = 0.244, p < 0.001), WHO grade (HR = 0.068, p < 0.001), TACC3 (HR = 0.169, p < 0.001), age (HR = 0.526, p = 0.004), Karnofsky performance score (KPS) (HR = 0.194, p < 0.001) were prognostic indicators for glioma patients.