In addition to HOTAIR, another putative chemoresistance lncRNA of particular interest is MRUL (NR_024549), since the chromosomal locus for MRUL is in close proximity to the locus for the Multi Drug Resistance 1 (MDR1) gene—the latter being recognised as the most important gene to induce cancer chemoresistance phenotypes [239]. The gene discussed is DMTF1; the disease is cancer.