In contrast, the abundance of Ifnb, Ifna4 or Cxcl10 mRNAs induced by RNA mimic poly(I:C) transfection (S2A Fig) or RNA virus Sendai virus (SeV) infection (Fig 1B, right panel) was comparable between Rnf185 knockdown and wild-type L929 cells. The gene discussed is IFNB1; the disease is infection.