We thank Dean Felsher for tet-o-MYC and LAPtTA mice; Hao Zhu for human HCC cells, Steve Kliewer for human SHP cDNA, David Mangelsdorf for SHP luciferase reporter plasmid, Joshua Mendell for Renilla luciferase plasmid, and John Shelton and the Molecular Pathology Core for assistance with PAS staining. The gene discussed is NR0B2; the disease is hepatocellular carcinoma.