The histopathology and echocardiographic results showed that similar to HDC−/− mice, STAT6−/− mice displayed worse cardiac remodeling and function than WT mice post-MI, as these mice had larger LVEDDs, LVESDs, LVEDVs, and LVESVs (Fig. 6d–f) and lower LVEFs and LVFSs than their counterparts (Fig. 6g). This evidence concerns the gene STAT6 and myocardial infarction.