Moreover, studies over the years have indicated that SChLAP1 expression is increased with prostate cancer progression and the level of SChLAP1 independently predict the poor clinical outcome in patients with localized prostate cancer following radical prostatectomy [74] and patients with lethal prostate cancer [76] through the analysis of hazard ratios (HRs) using multivariable Cox regression. This evidence concerns the gene SCHLAP1 and Familial prostate cancer.