VCAM1 and lung cancer: To investigate whether the VCAM-1-D6 domain plays a similar key role in the invasion of lung cancer cells, we prepared an Fc fusion protein of VCAM-1-D6 (VCAM-1-D6-Fc) and performed a competitive blocking experiment by treating A549 cells, grown in the presence of hTNFα with VCAM-1-D6-Fc, or Fc alone as a negative control.