To further confirm the specific inhibitory effect of VCAM-1-D6 huMab on lung cancer cell invasion, we treated A549 cells, cultured in the absence or presence of hTNFα, with VCAM-1-D6 huMab or a commercially available VCAM-1-D1 blocking antibody, and then we performed invasion assays. This evidence concerns the gene VCAM1 and lung carcinoma.