Meta-analysis results showed a significant association between TMEM187 rs13397 (OR = 1.56, 95% CI = 1.25–1.94, and p value < 0.0001) and IRAK1 rs1059702 (OR = 1.41, 95% CI = 1.11–1.80, and p value = 0.006) polymorphisms and susceptibility to RA (Figures 2(a) and 2(c)). This evidence concerns the gene IRAK1 and rheumatoid arthritis.