SERPINE1 and metabolic syndrome: A previous report from European based-sample population showed a positively and independently association between PAI-1 antigen levels and the presence of the Metabolic Syndrome according to the NCEP ATP-III criteria, reporting a median of 126 (81.4–194.2) ng/mL for those subjects with the Metabolic Syndrome versus 57.3 (35.5–99.7) ng/mL without it (p < 0.001) [19].