Interestingly, a significant positive correlation was found between expression of Syndecan-1 and CD44 in IBC (r = 0.87, P < 0.001) and in non-IBC (r = 0.54, P < 0.05) (Fig. 1c), suggesting a functional association and an essential role in IBC patients. The gene discussed is CD44; the disease is inflammatory breast carcinoma.