TNF and colitis: Two-way ANOVA (colitis x CORT treatment) showed a significant effect of colitis on IL-1β (F1,13 = 335.4, p<0.0001) and TNF-α (F1,13 = 422.2, p<0.0001) and a significant effect of CORT treatment on both cytokines expression (for IL-1β F1,13 = 257.9, p<0.0001; for TNF-α F1,13 = 362.3, p<0.0001) (Fig 4A and 4B).