Concerning the PK2 protein expression (Fig 5B), TNBS instillation significantly increased colonic PK2 in colitic animals with respect to healthy rats (colitis effect, F1,13 = 11.50, p<0.01) and CORT treatment significantly reduced PK2 expression in CORT-nursed rats, with respect to control group (CORT treatment effect, F1,13 = 8.16, p<0.05). The gene discussed is PROK2; the disease is colitis.