A previous study reported that the expression of cFos in excitatory neurons precedes its expression in inhibitory interneurons after the onset of behavioral seizures in a mouse model of epilepsy.45 Consistently, we observed that parvalbumin-positive GABAergic interneurons exhibited strong cFos immunoreactivity 4 h after KA administration, but only faint immunoreactivity at earlier time points. The gene discussed is FOS; the disease is epilepsy.