We have previously shown that in supposed healthy individuals the C allele of rs4416670 was positively associated with l-selectin mRNA, and that VEGF145 mRNA positively regulated l-selectin expression.21 At the same time, l-selectin has been shown to correlate with mental diseases such as the pathogenesis of schizophrenia22 and the severity of panic disorder,23 thus indicating that this molecule can play a significant role in these conditions. Here, SELL is linked to panic disorder.