RPGRIP1L and nervous system disorder: In summary, our studies revealed RPGRIP1L as a novel MyoVa-binding protein – the first to be demonstrated to interact with MyoVa at the centrosome – and uncover an unprecedented link between MyoVa and ciliogenesis, providing new perspectives for studies aiming to better understand why defects in MyoVa cause neurological disorders in Griscelli syndrome patients.