HMGN1 and B-cell acute lymphoblastic leukemia: In human, overexpression of HMGN1 (ENSG00000205581), a nucleosome remodelling protein encoded on chromosome 21q2240, suppresses histone 3 lysine 27 trimethylation (H3K27me3) and promotes both B cell proliferation in vitro and B cell acute lymphoblastic leukemia in vivo41.