CD274 and renal cell carcinoma: In Fig. 1D a Kaplan-Meier estimate is shown indicating a positive impact of the PD-L1 abundance (≥1% versus 0%) on overall survival (p = 0.045; Log-rank test), albeit supported by only few samples but in accordance to most evidences in ovarian cancer16, 17 which is in discordance to the impact of PD-L1 expression on survival in nearly all other cancer entities including gastric cancer, hepatocellular carcinoma, renal cell carcinoma, esophageal cancer, pancreatic cancer, and bladder cancer18.