On the one hand, melanomas with chronic sun-induced damage (CSD) harbor mutations in KIT proto-oncogene receptor tyrosine kinase (KIT, Gene ID: 3815), NF1, NRAS, and BRAF but typically not BRAF(V600E), the specific BRAF mutation that commonly arises in atypical melanocytic neoplasms [119, 120]. This evidence concerns the gene BRAF and melanoma.