In melanoma, highest ranking tumor suppressor genes are tumor protein p53 (TP53, Gene ID: 7157), neurofibromin 1 (NF1, Gene ID: 4763), AT-rich interaction domain 2 (ARID2, BAF200, Gene ID: 196528), AT-rich interaction domain 1A (ARID1A, BAF250, Gene ID: 8289), cyclin-dependent kinase inhibitor 2A (CDKN2A, P14ARF/P16INK4A, Gene ID: 1029), and phosphatase and tensin homolog (PTEN, Gene ID: 5728). This evidence concerns the gene NF1 and melanoma.