PVT1 has been reported to inhibit apoptosis and enhance tumorigenicity in colorectal cancer [37], promote cell proliferation and stem cell-like property in hepatocellular carcinoma [14, 31], promote tumorigenesis in lung cancer [35], promote cell proliferation and multidrug resistance in gastric cancer [33, 38], and promote cisplatin resistance in ovarian cancer [39]. This evidence concerns the gene PVT1 and lung cancer.