MALAT1 and hepatocellular carcinoma: These lncRNAs can act as promoters of HCC (e.g., the HOX Transcript Antisense Intergenic RNA HOTAIR, MALAT1, and HULC) [49–51] as well as tumor suppressors (e.g., p53 regulation-associated lncRNA PRAL and CPS1-IT1) [52, 53] and several of them are involved in epigenetic mechanisms of gene expression regulation [54].