MAP2K7 and cancer: Alcolea et al. reported (i) the emerging notion that cancer cells are not always dependent on single oncogenes, (ii) that markers of PI3K and MEK pathway activities are poor predictors of response to PI3K and MEK inhibitors, respectively, (iii) that kinase pathways can cooperate to drive cancer cells proliferation in some systems, and (iv) that a combination of inhibitors may be more effective in arresting cancer cell growth when compared to agents that target single kinases (126).