As previously recommended, most adults with type 1 or type 2 diabetes should undertake at least 150 min or more of moderate- to vigorous-intensity activity weekly; it is also recommended that these activities occur on at least 3 or more days during the week and that individuals should not allow more than 2 days to elapse between activity sessions to maintain higher levels of insulin sensitivity (Table 1). The gene discussed is INS; the disease is type 2 diabetes mellitus.