CD8A and coinfection: Similar results were obtained using time dependent multivariate models with the following changes, with respect to the main analysis: i) replacing CD4 cell count with CD4/CD8 ratio, ii) replacing antiretroviral therapy with HIV-RNA positivity, iii) including cancer occurrence as covariate, and iv) weighting model for losses to follow-up (data not shown), v) limiting the analysis to patients who started a cART, vi) stratified the analysis for presence of HBV or HCV coinfection.