HDAC9 and Stroke: Indeed, many non-selective HDAC inhibitors such as valproic acid (VPA) [20], suberoylanilide hydroxamic acid (SAHA) [26], 4-phenylbutyrate [27], sodium butyrate, and trichostatin A [19] have been tested in animal models of stroke and were shown to induce neuroprotection and reduce inflammation when administered within a few hours after stroke onset.