Furthermore, to study whether the expression of ITGA1 affecting the expression of ITGB1, we detected ITGB1 expression and found that there was no change in the expression of ITGB1 in ITGA1-overexpressed or ITGA1-silenced expression of HCC cells (Figure S2), which was consistent with a previous report by Pozzi A [25]. This evidence concerns the gene ITGB1 and hepatocellular carcinoma.