In this subgroup, divergence of the survival curves was seen for ER positive tumors (five-year OCSS 89.0%, standard error 3.3%) compared to ER negative tumor (five-year OCSS 84.6%, standard error 12.0%, log rank p = 0.053), PR positive tumors (five-year OCSS 89.9%, standard error 3.2%) compared to PR negative tumor (five-year OCSS 80%, standard error 12.6%, log rank p = 0.11) and ER + PR positive tumors (five-year OCSS 89.5%, standard error 3.3%) compared to ER + PR negative tumor (five-year OCSS 80%, standard error 12.6%, log rank p = 0.11). This evidence concerns the gene ESR1 and neoplasm.