Quantitative PCR analysis of a small number of colon tumors from Rint1+/-; ApcMin/+ mice indicated that the wild type allele of Rint1 was not lost somatically in these tumors (data not shown) and Rint1 expression is not reduced in colon tumors in ApcMin/+ mice (Fig 2D). This evidence concerns the gene RINT1 and colonic neoplasm.