By contrast, 6.1% (37 of 607) of colorectal tumors in the COSMIC database overexpressed RINT1. Likewise, comparison of colorectal cancers and normal mucosa in the Oncomine database showed that RINT1 transcript levels were significantly greater in many colon adenocarcinoma subtypes (Fig 3A). Here, RINT1 is linked to colorectal cancer.