RINT1 and neoplasm: Because the Rint1 knockout allele is tightly linked to the 129 allele of Mom5, which is associated with reduced tumor multiplicity in ApcMin/+ mice, to assess the impact of heterozygosity for the Rint1 knockout on tumorigenesis in ApcMin/+ mice, we needed to compare Rint1+/-;Mom5129/B6;ApcMin/+mice with Rint1+/+;Mom5129/B6;ApcMin/+ mice.