Western blotting of 12 HNSCC tumours consistently showed a significantly positive correlation of GATA3 with HIF-1α and GATA3 with SLC2A1, a well-known HIF-1 target (Pearson’s correlation coefficient=0.65 and 0.64, respectively, P<0.05; Supplementary Figure S5c). This evidence concerns the gene GATA3 and neoplasm.