GATA3 expression is associated with favourable disease-free and overall survivals in breast cancers.10 However, GATA3 is a poor prognostic marker in neuroblastomas, endometrial carcinomas and soft tissue sarcomas.11, 12, 14 The underlying mechanisms of the distinct function of GATA3 still remain unclear. This evidence concerns the gene GATA3 and neuroblastoma.