Given the role of the NLRP3 inflammasome and recent data proving the efficacy of OM-85 in controlling influenza infection, it is conceivable that part of the protective effect of OM-85 is mediated by priming of the inflammasome–IL-1 axis16, 23, 24, 25, 26, 27, 56. Here, NLRP3 is linked to ocular melanoma.