Data analysis and ranking of the top 5 HKGs using geNorm and Normfinder (Supplementary Table S15) identified UBC, TBP, IPO8, TFRC, GAPDH in head and neck cancer; TBP, IPO8, GUSB, UBC in lung and TBP, IPO8, TFRC, GUSB, HMBS in pancreas to be stable. The gene discussed is TBP; the disease is head and neck cancer.