BDNF and kidney disorder: Shown in the enrichment analysis outlined in Figure S7, these pathways include the leptin signaling pathway, which accounted for the reversibility of WT-1 in a mouse nephropathy model70; BDNF, which was shown to repair podocyte damage and restore the expression of nephrin71; and the EPO signaling pathway that has a renoprotective effect against loss of nephrin72.