ZEB1 and colorectal carcinoma: In order to confirm that miR-139-5p, a noncoding RNA, regulates EMT-related genes (ZEB1, ZEB2, E-cadherin), we overexpressed miR-139-5p by transiently transfecting CRC cell lines with miR-139-5p mimics or scrambled controls, and evaluated the protein expression of these downstream target genes.