To begin to elucidate the underlying biology of the Bcor-mutant lymphomas we applied RNA-seq analysis of Eμ-Myc lymphomas with shRNA-mediated knockdown of Bcor (Eμ-Myc;shBcor, n=6) or Trp53 (Eμ-Myc;shp53, n=6); or Eμ-Myc lymphomas overexpressing NrasQ61K (Eμ-Myc;NrasQ61K, n=5). Here, MYC is linked to lymphoma.