Further WES analysis of six Eμ-Myc;Cdkn2a+/− lymphomas revealed that all had lost the wild type Cdkn2a allele and one lymphoma harboured a heterozygous pathogenic KrasQ61H mutation (VAF=67%), indicating selective outgrowth of an Eμ-Myc lymphoma with loss of INK4A/ARF and expression of oncogenic Kras (Supplementary Fig. 10 and Supplementary Data 4). Here, KRAS is linked to lymphoma.