Current evidences suggest that positive family history of CAD and different alterations in lipid metabolism, including high low density lipoprotein cholesterol (LDL-c) and low high density lipoprotein cholesterol (HDL-c) levels (both separately and jointly), high triglyceride (TG) levels, high apoB levels, high lipoprotein (a) (Lp(a)) levels, are important risk factors for CAD. Here, APOB is linked to coronary artery disorder.