A common Adenine (A) to Thymine (T) substitution at 347 bp in the ApoA-IV gene (also known as 347A > T, Thr347Ser polymorphism) has been shown to be associated with lower plasma levels of Apo AIV and higher incidences of CAD in some studies (Wong et al., 2003). Here, APOA4 is linked to coronary artery disorder.