Here, we tested whether AT1R expressed in Plasmodium-specific CD8+ T cells modulates the expression of molecules involved in the migration and sequestration of pathogenic CD8+ T cells in inflamed tissues during severe malaria, such as LFA-1 (CD11a), CCR5, and CXCR3 (Falanga and Butcher, 1991; Belnoue, 2003; Sarfo et al., 2004; Hansen et al., 2007; Nie et al., 2009). This evidence concerns the gene ITGAL and malaria.