CD8A and malaria: Because MHC I-restricted epitopes of Plasmodium antigens during blood-stage malaria were not known, transgenic lineages of parasites expressing model epitopes, for which T-cell receptor (TCR) transgenic mice are available, were generated to study the immune response of antigen-specific CD8+ T cells (Lundie et al., 2008; Miyakoda et al., 2008).