Our results on cultured C-neu/HER2 cells incubated with 0.5 mM β-OHB (approximately the concentration that we had found in solid tumours) showed that the cells took up 0.26 ± 0.71 μmol β-OHB/106 cells/24 h, implying that metabolism of β-OHB would indeed have reduced its concentration in the tumours (Table 2). This evidence concerns the gene ERBB2 and neoplasm.